Liquid biopsy in cancer – Currently available blood tests for cancer – OncoK9 – Antech

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Currently available blood tests for cancer

OncoK9 – Antech

Published 29 May 2025

This test uses Next Generation Sequencing (NGS) and is claimed to be able to detect changes associated with 30 types of canine cancer, including lymphoma, hemangiosarcoma, soft tissue sarcoma, mast cell tumor, osteosarcoma, mammary gland carcinoma, anal sac adenocarcinoma, and malignant melanoma. (OncoK9® — The Liquid Biopsy Test for Dogs™ [AntechTM] [online]. Available from: https://antechdiagnostics.co.uk/oncok9/ [Accessed 29 May 2025]

  • Flory, A. et al. (2022) Clinical validation of a next-generation sequencing-based multi-cancer early detection “liquid biopsy” blood test in over 1,000 dogs using an independent testing set: The CANcer Detection in Dogs (CANDiD) study. PLOS ONE, 17 (4), e0266623. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0266623
  • Flory, A. et al. (2023) Cancer detection in clinical practice and using blood‐based liquid biopsy: A retrospective audit of over 350 dogs. Journal of Veterinary Internal Medicine, 37 (1), pp. 258-267. https://doi.org/10.1111/jvim.16616
  • O’Kell, A.L. et al. (2023) Clinical experience with next-generation sequencing–based liquid biopsy testing for cancer detection in dogs: a review of 1,500 consecutive clinical cases. Journal of the American Veterinary Medical Association, 261 (6), pp. 827-836. https://doi.org/10.2460/javma.22.11.0526
  • Flory, A. et al. (2024) Clinical validation of a blood-based liquid biopsy test integrating cell-free DNA quantification and next-generation sequencing for cancer screening in dogs. Journal of the American Veterinary Medical Association, 262 (5), pp. 665-673. https://doi.org/10.2460/javma.23.10.0564

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