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Tag: osteoarthritis
Rabbit in vet surgery

Incidental osteoarthritis: risk factors, prevalence and clinical evidence in rabbits

Bagha, F. and Keeble, E. | Companion Animal | February 2024
The aim of this retrospective study was to evaluate the risk factors, prevalence, and clinical evidence of appendicular osteoarthritis in pet rabbits…

Equine umbilical cord mesenchymal stem cells demonstrate safety and efficacy in the treatment of canine osteoarthritis: a randomized placebo-controlled trial

| Journal of the American Veterinary Medical Association | 2022 | The aim of this blinded, randomised and placebo-controlled study, was to demonstrate the efficacy and safety of equine umbilical cord mesenchymal stem cells (available in the UK as Dogstem) in the management of dogs with osteoarthritis…

Dog resting

COAST Development Group’s international consensus guidelines for the treatment of canine osteoarthritis

Cachon, T., Frykman, O., Innes, J.F., Lascelles, B.D.X., Okumura, M., Sousa, P., Staffieri, F., Steagall, P.V. and Van Ryssen, B. | Frontiers in Veterinary Science | August 2023
The aim of the COAST Development Group’s consensus guidelines for the treatment of canine osteoarthritis (OA) is to provide an evidence-based reference resource to support veterinary practitioners with the development of tailored OA management and treatment plans based on the OA stage of individual patients…

Veterinarian doctor examining the leg of a cat

Frunevetmab, a felinized anti-nerve growth factor monoclonal antibody, for the treatment of pain from osteoarthritis in cats

M.E. Gruen, J.A.E. Myers, J-K.S. Tena, C. Becskei, D.M. Cleaver and B.D.X. Lascelles | Journal of Veterinary Internal Medicine | November/December 2021
The aim of this randomised, placebo-controlled, double-blind study was to evaluate the efficacy of frunevetmab, a felinized anti-nerve growth factor monoclonal antibody in cats with naturally occurring osteoarthritic (OA) pain…

Efficacy and safety of enflicoxib for treatment of canine osteoarthritis

| Veterinary Record | 2021 | The objective of this prospective randomised controlled trial was to confirm the safety and efficacy of enflicoxib for the treatment of naturally occurring osteoarthritis (OA) in dogs …

Efficacy and safety of enflicoxib for treatment of canine osteoarthritis: A 6-week randomised, controlled, blind, multicentre clinical trial

M. Salichs, L. Badiella, P. Sarasola and J. Homedes | Veterinary Record | September 2021
The aim of this prospective randomised controlled trial was to confirm the safety and efficacy of enflicoxib for the treatment of naturally occurring osteoarthritis (OA) in dogs…

Vet examining a dog in a clinic

A prospective, randomized, blinded, placebo-controlled multisite clinical study of bedinvetmab , a canine monoclonal antibody targeting nerve growth factor, in dogs with osteoarthritis

M.J. Corral, H. Moyaert, T. Fernandes, M. Escalada, J.K.S. Tena, R. R. Walters and M.R. Stegemann | Veterinary Anaesthesia and Analgesia | August 2021
The aim of this randomized, double-blind, multicentre study was to evaluate the efficacy and safety of bedinvetmab (Librela; Zoetis), compared to a placebo, for the alleviation of pain associated with osteoarthritis in client-owned dogs (n = 287)…

A Golden Retriever lying on a bed

Laboratory safety evaluation of bedinvetmab, a canine anti-nerve growth factor monoclonal antibody, in dogs

M. Krautmann, R. Walters, P. Cole, J. Tena, L.M. Bergeron, J. Messamore, D. Mwangi, S. Rai, P. Dominowski, K. Saad, Y. Zhu, M. Guillot and L. Chouinard | The Veterinary Journal | October 2021
This paper describes the laboratory safety evaluation of bedinvetmab based on three integrated laboratory studies in healthy adult laboratory Beagles…

cat on the stairs

Efficacy and safety of an anti-nerve growth factor antibody (Frunevetmab) for the treatment of degenerative joint disease-associated chronic pain in cats: A multisite pilot field study

M.E. Gruen, J.A.E. Myers and B. D. X. Lascelles | Frontiers in Veterinary Science | May 2021
The aim of this randomised placebo-controlled, double-blinded trial was to evaluate the safety and efficacy of two administration routes of frunevetmab compared to placebo in the treatment of degenerative joint disease (DJD)-associated pain in client-owned cats…

Old cat looking to something

2021 AAFP Feline Senior Care Guidelines

M. Ray, H.C. Carney, B. Boynton, J. Quimby, S. Robertson, K. St Denis, H. Tuzio and B. Wright | Journal of Feline Medicine and Surgery | June 2021
These consensus guidelines provide information for practitioners on all aspects of the care of senior cats…