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Determination of a safe sedative combination of dexmedetomidine, ketamine and butorphanol for minor procedures in dogs by use of a stepwise optimization method

Imboden, T.J., Pownall, W.R., Rubin, S., Spadavecchia, C., Schöllhorn, B. and Rohrbach, H. | Acta Veterinaria Scandinavica | September 2023
The aim of this randomised three-phase controlled trial was to determine the optimal dosages of dexmedetomidine and ketamine in combination with butorphanol 0.3 mg/kg in terms of the quality of sedation, side effects, and the need for additional anaesthetics…