cannabidiol safety and toxicity: dogs and cats

spotlight topic:

Dogs and cats

Published 21 April 2023 | Updated 15 May 2024

  • Limsuwan, S. et al. (2024) Pharmacokinetics behavior of four cannabidiol preparations following single oral administration in dogs. Frontiers in Veterinary Science, 11.
  • Binagia, E. M., Gregory, E. A., and Yankin, I. (2024) Clinical examination findings and electrolyte abnormalities of dogs with marijuana/tetrahydrocannabinol toxicity: 223 cases (January 2017–July 2021). Journal of the American Veterinary Medical Association.
  • Bookout, W. et al. (2024) Safety study of cannabidiol products in healthy dogs. Frontiers in Veterinary Science, 11.
  • Coltherd, J.C. et al. (2024) Healthy cats tolerate long-term daily feeding of Cannabidiol. Frontiers in Veterinary Science, 10.
  • Jost, H.E. et al. (2023) Long-term effect of oral cannabidiol administration to healthy adult dogs on tear production, intraocular pressure, and tear concentrations. Veterinary Ophthalmology.
  • Bradley, S. et al. (2022) Long-term daily feeding of cannabidiol is well-tolerated by healthy dogs. Frontiers in Veterinary Science, 9.
  • Morris, E.M. et al. (2021) Feeding cannabidiol (CBD)-containing treats did not affect canine daily voluntary activity. Frontiers in Veterinary Science, 8.
  • Vaughn, D.M., Paulionis, L.J. and Kulpa, J.E. (2021) Randomized, placebo-controlled, 28-day safety and pharmacokinetics evaluation of repeated oral cannabidiol administration in healthy dogs. American Journal of Veterinary Research, 82 (5), pp. 405-416.
  • Kulpa, J.E. et al. (2021) Safety and tolerability of escalating cannabinoid doses in healthy cats. Journal of Feline Medicine and Surgery23 (12), pp. 1162-1175.
  • Brutlag, A. and Hommerding, H. (2018) Toxicology of marijuana, synthetic cannabinoids, and cannabidiol in dogs and cats. Veterinary Clinics: Small Animal Practice, 48 (6), pp. 1087-1102.
  • Simpson, A.C., Bradley, C.W. and Schissler, J.R. (2020) Probable cutaneous adverse drug reaction due to a cannabidiol‐containing hemp oil product in a dog. Veterinary Dermatology, 31 (5), pp. 404-e108.
  • McGrath, S. et al. (2018) A report of adverse effects associated with the administration of cannabidiol in healthy dogs. Journal of the American Holistic Veterinary Medicine Association. 52, 34-38


Updated 15 May 2024

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