cannabidiol safety and toxicity: dogs and cats
spotlight topic:
Dogs and cats
Published 21 April 2023 | Updated 9 August 2024
- Mills, T. et al. (2024) Tolerability of 2 and 4 mg/kg dosing every 12 hour of a cannabidiol- and cannabidiolic acid-rich hemp extract on mixed-breed dogs utilized for teaching in a closed colony. Animals, 14 (13):1863. https://doi.org/10.3390/ani14131863
- Limsuwan, S. et al. (2024) Pharmacokinetics behavior of four cannabidiol preparations following single oral administration in dogs. Frontiers in Veterinary Science, 11. https://doi.org/10.3389/fvets.2024.1389810
- Binagia, E. M., Gregory, E. A., and Yankin, I. (2024) Clinical examination findings and electrolyte abnormalities of dogs with marijuana/tetrahydrocannabinol toxicity: 223 cases (January 2017–July 2021). Journal of the American Veterinary Medical Association. https://doi.org/10.2460/javma.24.02.0092
- Bookout, W. et al. (2024) Safety study of cannabidiol products in healthy dogs. Frontiers in Veterinary Science, 11. https://doi.org/10.3389/fvets.2024.1349590
- Coltherd, J.C. et al. (2024) Healthy cats tolerate long-term daily feeding of Cannabidiol. Frontiers in Veterinary Science, 10. https://www.frontiersin.org/articles/10.3389/fvets.2023.1324622
- Jost, H.E. et al. (2023) Long-term effect of oral cannabidiol administration to healthy adult dogs on tear production, intraocular pressure, and tear concentrations. Veterinary Ophthalmology. https://doi.org/10.1111/vop.13164
- Bradley, S. et al. (2022) Long-term daily feeding of cannabidiol is well-tolerated by healthy dogs. Frontiers in Veterinary Science, 9. https://doi.org/10.3389%2Ffvets.2022.977457
- Morris, E.M. et al. (2021) Feeding cannabidiol (CBD)-containing treats did not affect canine daily voluntary activity. Frontiers in Veterinary Science, 8. https://doi.org/10.3389/fvets.2021.645667
- Vaughn, D.M., Paulionis, L.J. and Kulpa, J.E. (2021) Randomized, placebo-controlled, 28-day safety and pharmacokinetics evaluation of repeated oral cannabidiol administration in healthy dogs. American Journal of Veterinary Research, 82 (5), pp. 405-416. https://doi.org/10.2460/ajvr.82.5.405
- Kulpa, J.E. et al. (2021) Safety and tolerability of escalating cannabinoid doses in healthy cats. Journal of Feline Medicine and Surgery, 23 (12), pp. 1162-1175. https://doi.org/10.1177/1098612X211004215
- Brutlag, A. and Hommerding, H. (2018) Toxicology of marijuana, synthetic cannabinoids, and cannabidiol in dogs and cats. Veterinary Clinics: Small Animal Practice, 48 (6), pp. 1087-1102. https://doi.org/10.1016/j.cvsm.2018.07.008
- Simpson, A.C., Bradley, C.W. and Schissler, J.R. (2020) Probable cutaneous adverse drug reaction due to a cannabidiol‐containing hemp oil product in a dog. Veterinary Dermatology, 31 (5), pp. 404-e108. https://doi.org/10.1111/vde.12876
- McGrath, S. et al. (2018) A report of adverse effects associated with the administration of cannabidiol in healthy dogs. Journal of the American Holistic Veterinary Medicine Association. 52, 34-38 https://www.ahvma.org/wp-content/uploads/AHVMA-2018-V52-CannabisAdverseEffects.pdf
Horses
Updated 15 May 2024
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