Cannabidiol: Pain management and osteoarthritis

spotlight topic:

Pain management and osteoarthritis

Published 23 April 2023 | Updated 15 March 2024

  • Interlandi. C. et al. (2024) Improved quality of life and pain relief in mature horses with osteoarthritis after oral transmucosal cannabidiol oil administration as part of an analgesic regimen. Frontiers in Veterinary Science, 11.
  • Miranda-Cortés, A. et al. (2022) The role of cannabinoids in pain modulation in companion animals. Frontiers in Veterinary Science, 9.
  • Morrow, L. and Belshaw, Z. (2022) Cannabidiol (CBD) in addition to current treatment for pain reduction in canine osteoarthritis [BestBETs for Vets] [online]. Available from: [Accessed 6 April 2023]
  • Patikorn, C. et al. (2023) Efficacy and safety of cannabidiol for the treatment of canine osteoarthritis: a systematic review and meta-analysis of animal intervention studies. Frontiers in Veterinary Science, 10, 1248417.
  • Shilo-Benjamini, Y. et al. (2023) Therapeutic efficacy and pharmacokinetics of liposomal-cannabidiol injection: a pilot clinical study in dogs with naturally-occurring osteoarthritis. Frontiers in Veterinary Science, 10.
  • Brioschi, F.A. et al. (2020) Oral transmucosal cannabidiol oil formulation as part of a multimodal analgesic regimen: Effects on pain relief and quality of life improvement in dogs affected by spontaneous osteoarthritis. Animals, 10 (9), no. 1505.
  • Gamble, L.J. et al. (2018) Pharmacokinetics, safety, and clinical efficacy of cannabidiol treatment in osteoarthritic dogs. Frontiers in Veterinary Science, 5.
  • Verrico, C.D. et al. (2020) A randomized, double-blind, placebo-controlled study of daily cannabidiol for the treatment of canine osteoarthritis pain. Pain, 161 (9), pp. 2191-2202.
  • Klatzkow, S. et al. (2022) Evaluation of the efficacy of a cannabidiol and cannabidiolic acid rich hemp extract for pain in dogs following a tibial plateau leveling osteotomy. Frontiers in Veterinary Science, 9.

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