Stem cells – what is the evidence: Small animal

spotlight topic:

Small animal

Published 13 May 2025

  • Kang, M.H. and Park, H.M. (2020) Challenges of stem cell therapies in companion animal practice. Journal of Veterinary Science, 21 (3). https://doi.org/10.4142/jvs.2020.21.e42
  • Webb, T.L. (2020) Stem cell therapy and cats: what do we know at this time. Veterinary Clinics of North America: Small Animal Practice, 50 (5), pp. 955-971. https://doi.org/10.1016/j.cvsm.2020.06.002
  • Quimby, J.M. (2019) Stem cell therapy. Veterinary Clinics of North America: Small Animal Practice, 49 (2), pp. 223-231. https://doi.org/10.1016/j.cvsm.2018.10.001
  • Wang, Y. et al. (2023) Stem cell terapy for aging related diseases and joint diseases in companion animals. Animals, 13 (15), no. 2457. https://doi.org/10.3390/ani13152457
  • Jeung, S. et al. (2024) Safety and efficacy of canine gonadal tissue-derived mesenchymal stem cells for early myxomatous mitral valve disease. Frontiers in Veterinary Science, 11. https://doi.org/10.3389/fvets.2024.1404607
  • Cho, H.S. et al. (2024) Intravenous injection of allogenic canine mesenchymal stem cells in 40 client-owned dogs: a safety assessment in veterinary clinical trials. BMC Veterinary Research, 20, no. 375 https://doi.org/10.1186/s12917-024-04216-3
  • Armitage, A.J. et al. (2023) Efficacy of autologous mesenchymal stromal cell treatment for chronic degenerative musculoskeletal conditions in dogs: A retrospective study. Frontiers in Veterinary Science, 9, no. 1014687. https://doi.org/10.3389/fvets.2022.1014687
  • Moloney, M. (2022) In dogs with osteoarthritis, is intra-articular allogenic mesenchymal stem cell therapy more effective than placebo effect? Veterinary Evidence, 7 (3). https://doi.org/10.18849/ve.v7i3.473
  • Kim, T.-Y. et al. (2025) Evaluation of cognitive and mobility function in geriatric dogs following treatment with stem cell and stem cell extracellular vesicles derived from embryonic stem cells: a pilot study. Frontiers in Veterinary Science, 12. https://doi.org/10.3389/fvets.2025.1549870
  • Nekouei, O. et al. (2024) Effectiveness of mesenchymal stem cell therapy in cats with chronic gingivostomatitis. Veterinary Evidence, 9 (1). https://doi.org/10.18849/ve.v9i1.680
  • Olsson, D.C. et al. (2021) Administration of mesenchymal stem cells from adipose tissue at the hip joint of dogs with osteoarthritis: A systematic review. Research in Veterinary Science, 135, pp. 495-503. https://doi.org/10.1016/j.rvsc.2020.11.014
  • Kiefer, K. M. et al. (2016) Does adipose-derived stromal cell adjuvant therapy for fragmented medial coronoid process in dogs influence outcome? A pilot project. Veterinary Evidence, 1 (4). https://doi.org/10.18849/ve.v1i4.45

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