Stem cells – what is the evidence: Currently licensed products in the UK: RenuTend

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Published 26 February 2024 | updated 15 March 2024

RenuTend suspension for injection for horses contains tenogenic primed equine allogeneic peripheral blood-derived mesenchymal stem cells and is indicated “To restore fibre alignment in horses with superficial digital flexor tendon or suspensory ligament fibre disruption”.

Veterinary Medicines Directorate (2022) Summary of Product Characteristics: RenuTend suspension for injection for horses. Available from: (Accessed 26 February 2024)

  • Stephanie, C. et al. (2024) Safety assessment of equine allogeneic tenogenic primed mesenchymal stem cells in horses with naturally occurring tendon and ligament injuries. Frontiers in Veterinary Science, 11, no. 1282697.
  • Depuydt, E. et al. (2022) Cellular and humoral immunogenicity investigation of single and repeated allogeneic Tenogenic primed mesenchymal stem cell treatments in horses suffering from tendon injuries. Frontiers in Veterinary Science8, no. 789293.
  • Carlier, S. et al. (2023) Equine allogeneic tenogenic primed mesenchymal stem cells: A clinical field study in horses suffering from naturally occurring superficial digital flexor tendon and suspensory ligament injuries. Equine Veterinary Journal.

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