Cannabidiol: Pain management and osteoarthritis

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Pain management and osteoarthritis

Published 23 April 2023 | Updated 20 September 2024

  • K. Soontornvipart, P. et al. (2024) Cannabidiol plus krill oil supplementation improves chronic stifle osteoarthritis in dogs: A double-blind randomized controlled trial. The Veterinary Journal, 308. https://doi.org/10.1016/j.tvjl.2024.106227
  • Zanelli, G.R. et al. (2024) Perioperative analgesic and sedative effects of cannabidiol in cats undergoing ovariohysterectomy. Animals, 14 (16), no. 2286. https://doi.org/10.3390/ani14162286
  • Casas-Alvarado, A. et al. (2024) Assessment of the nociceptive response to the use of cannabidiol alone and in combination with meloxicam through infrared pupillometry in female dogs undergoing elective ovariohysterectomy. Frontiers in Veterinary Science, 11. https://doi.org/10.3389/fvets.2024.1380022
  • Panda, C. et al. (2024) Efficacy and tolerability of full spectrum hemp oil in dogs living with pain in common household settings. Frontiers in Veterinary Science, 11. https://doi.org/10.3389/fvets.2024.1384168
  • Hasckel Gewehr, J.L. et al. (2024) Full spectrum cannabidiol-rich extract reduced propofol dosage required for anesthetic induction in dogs—a pilot study. Frontiers in Veterinary Science, 11. https://doi.org/10.3389/fvets.2024.1352314
  • Interlandi. C. et al. (2024) Improved quality of life and pain relief in mature horses with osteoarthritis after oral transmucosal cannabidiol oil administration as part of an analgesic regimen. Frontiers in Veterinary Science, 11. https://www.frontiersin.org/articles/10.3389/fvets.2024.1341396
  • Miranda-Cortés, A. et al. (2022) The role of cannabinoids in pain modulation in companion animals. Frontiers in Veterinary Science, 9. https://doi.org/10.3389/fvets.2022.1050884
  • Morrow, L. and Belshaw, Z. (2022) Cannabidiol (CBD) in addition to current treatment for pain reduction in canine osteoarthritis [BestBETs for Vets] [online]. Available from: https://bestbetsforvets.org/bet/582 [Accessed 6 April 2023]
  • Patikorn, C. et al. (2023) Efficacy and safety of cannabidiol for the treatment of canine osteoarthritis: a systematic review and meta-analysis of animal intervention studies. Frontiers in Veterinary Science, 10, 1248417. https://doi.org/10.3389/fvets.2023.1248417.
  • Shilo-Benjamini, Y. et al. (2023) Therapeutic efficacy and pharmacokinetics of liposomal-cannabidiol injection: a pilot clinical study in dogs with naturally-occurring osteoarthritis. Frontiers in Veterinary Science, 10. https://doi.org/10.3389/fvets.2023.1224452
  • Brioschi, F.A. et al. (2020) Oral transmucosal cannabidiol oil formulation as part of a multimodal analgesic regimen: Effects on pain relief and quality of life improvement in dogs affected by spontaneous osteoarthritis. Animals, 10 (9), no. 1505. https://doi.org/10.3390/ani10091505
  • Gamble, L.J. et al. (2018) Pharmacokinetics, safety, and clinical efficacy of cannabidiol treatment in osteoarthritic dogs. Frontiers in Veterinary Science, 5. https://doi.org/10.3389/fvets.2018.00165
  • Verrico, C.D. et al. (2020) A randomized, double-blind, placebo-controlled study of daily cannabidiol for the treatment of canine osteoarthritis pain. Pain, 161 (9), pp. 2191-2202. https://doi.org/10.1097%2Fj.pain.0000000000001896
  • Klatzkow, S. et al. (2022) Evaluation of the efficacy of a cannabidiol and cannabidiolic acid rich hemp extract for pain in dogs following a tibial plateau leveling osteotomy. Frontiers in Veterinary Science, 9. https://doi.org/10.3389%2Ffvets.2022.1036056

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