Update on feline infectious peritonitis: Antiviral drugs

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Antiviral drugs

Published 27 September 2023

The protease inhibitor, GC376, which is able to inhibit viral replication in feline infectious peritonitis (FIP) was shown to have some effect but was not able to achieve remission in all cats.

The nucleoside analogues remdesivir and GS-441524 (the active form of the pro-drug remdesivir) have been legally available to vets in the UK for the treatment of FIP in cats since August 2021. The literature around these products has evolved rapidly and there are now longer term follow up studies and clinical trials being published.

A Knowledge Summary, published in Veterinary Evidence, concludes that there is now moderate evidence that these products can extend the survival time of cats suffering from feline infectious peritonitis. Further evidence will be added to this section as it is published.

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