Stem cells – what is the evidence: Currently licensed products in the UK: DogStem

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Published 26 February 2024

Dogstem suspension for injection into dogs contains equine umbilical cord mesenchymal stem cell and is indicated for “Improvement in function, reduction of pain and lameness associated with mild to severe osteoarthritis in hip and elbow joints”.

Veterinary Medicines Directorate (2022) Summary of Product Characteristics: DogStem suspension for injection for dogs. Available from: [Accessed 26 February 2024]

  • Punzón, E. et al. (2022) Equine umbilical cord mesenchymal stem cells demonstrate safety and efficacy in the treatment of canine osteoarthritis: a randomized placebo-controlled trial. Journal of the American Veterinary Medical Association260 (15), pp. 1947-1955.
  • Punzón, E. et al. (2023) Local, systemic and immunologic safety comparison between xenogeneic equine umbilical cord mesenchymal stem cells, allogeneic canine adipose mesenchymal stem cells and placebo: a randomized controlled trial. Frontiers in Veterinary Science10, no. 1098029.

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