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Prediction of clinically important acquired cardiac disease without an echocardiogram in large breed dogs using a combination of clinical, radiographic and electrocardiographic variables

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S. Wesselowski, S.G. Gordon, N. Meddaugh, A.B. Saunders, J. Häggström, K. Cusack, B.W. Janacek and D.J. Matthews | Journal of Veterinary Cardiology | August 2021
The objectives of this retrospective study were to (1) assess the clinical utility of thoracic radiographs and (2) to explore the potential utility of prediction models incorporating radiographic measurements, physical examination (PE) and electrocardiogram (ECG) to predict clinically important dilated cardiomyopathy (DCM) or myxomatous mitral valve disease (MMVD) in the absence of an echocardiogram in large-breed (LB) dogs…

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Vet examining a dog in a clinic

A prospective, randomized, blinded, placebo-controlled multisite clinical study of bedinvetmab , a canine monoclonal antibody targeting nerve growth factor, in dogs with osteoarthritis

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M.J. Corral, H. Moyaert, T. Fernandes, M. Escalada, J.K.S. Tena, R. R. Walters and M.R. Stegemann | Veterinary Anaesthesia and Analgesia | August 2021
The aim of this randomized, double-blind, multicentre study was to evaluate the efficacy and safety of bedinvetmab (Librela; Zoetis), compared to a placebo, for the alleviation of pain associated with osteoarthritis in client-owned dogs (n = 287)…

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A Golden Retriever lying on a bed

Laboratory safety evaluation of bedinvetmab, a canine anti-nerve growth factor monoclonal antibody, in dogs

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M. Krautmann, R. Walters, P. Cole, J. Tena, L.M. Bergeron, J. Messamore, D. Mwangi, S. Rai, P. Dominowski, K. Saad, Y. Zhu, M. Guillot and L. Chouinard | The Veterinary Journal | October 2021
This paper describes the laboratory safety evaluation of bedinvetmab based on three integrated laboratory studies in healthy adult laboratory Beagles…

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