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Veterinarian doctor examining the leg of a cat

Frunevetmab, a felinized anti-nerve growth factor monoclonal antibody, for the treatment of pain from osteoarthritis in cats

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M.E. Gruen, J.A.E. Myers, J-K.S. Tena, C. Becskei, D.M. Cleaver and B.D.X. Lascelles | Journal of Veterinary Internal Medicine | November/December 2021
The aim of this randomised, placebo-controlled, double-blind study was to evaluate the efficacy of frunevetmab, a felinized anti-nerve growth factor monoclonal antibody in cats with naturally occurring osteoarthritic (OA) pain…

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Vet examining a dog in a clinic

A prospective, randomized, blinded, placebo-controlled multisite clinical study of bedinvetmab , a canine monoclonal antibody targeting nerve growth factor, in dogs with osteoarthritis

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M.J. Corral, H. Moyaert, T. Fernandes, M. Escalada, J.K.S. Tena, R. R. Walters and M.R. Stegemann | Veterinary Anaesthesia and Analgesia | August 2021
The aim of this randomized, double-blind, multicentre study was to evaluate the efficacy and safety of bedinvetmab (Librela; Zoetis), compared to a placebo, for the alleviation of pain associated with osteoarthritis in client-owned dogs (n = 287)…

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A Golden Retriever lying on a bed

Laboratory safety evaluation of bedinvetmab, a canine anti-nerve growth factor monoclonal antibody, in dogs

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M. Krautmann, R. Walters, P. Cole, J. Tena, L.M. Bergeron, J. Messamore, D. Mwangi, S. Rai, P. Dominowski, K. Saad, Y. Zhu, M. Guillot and L. Chouinard | The Veterinary Journal | October 2021
This paper describes the laboratory safety evaluation of bedinvetmab based on three integrated laboratory studies in healthy adult laboratory Beagles…

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cat on the stairs

Efficacy and safety of an anti-nerve growth factor antibody (Frunevetmab) for the treatment of degenerative joint disease-associated chronic pain in cats: A multisite pilot field study

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M.E. Gruen, J.A.E. Myers and B. D. X. Lascelles | Frontiers in Veterinary Science | May 2021
The aim of this randomised placebo-controlled, double-blinded trial was to evaluate the safety and efficacy of two administration routes of frunevetmab compared to placebo in the treatment of degenerative joint disease (DJD)-associated pain in client-owned cats…

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BEVA primary care clinical guidelines: Analgesia

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I.M. Bowen, A. Redpath, A. Dugdale, J.H. Burford, D. Lloyd, T. Watson and G.D. Hallowell | Equine Veterinary Journal | October 2019
The aim of these clinical guidelines is to provide recommendations on the use of analgesia in the horse in clinical practice. These guidelines are based on the most recent evidence combined with expert clinical opinion on the impact of analgesic choice on outcomes and adverse events…

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